Druggable phosphatases in cancer and immune cells, with examples of their corresponding drugs. Structures of allosteric inhibitors targeting PP2A, PRL3, DUSP1/6, and SHP2 in cancer cells (left).
Scientists have discovered why ovarian cancer spreads so rapidly through the abdomen. Cancer cells enlist normally protective abdominal cells, forming mixed groups that work together to invade new ...
Colorectal tumors that underwent somatic next-generation sequencing (NGS) for 154-168 genes in an in-house laboratory between 2015 and 2022 were retrospectively identified. Microsatellite instability ...
Researchers say they are making progress tackling pancreatic cancer tumors.
An experimental drug combination was able to effectively treat pancreatic cancer in mouse models without tumor resistance.
Laboratory studies suggest cinnamon’s bioactive compounds can alter key cancer-related signaling pathways, but researchers caution that human trials are essential before any preventive or therapeutic ...
How this fungus influences the development of melanoma cells has for the first time been explained by the MicrobiomicsEHU ...
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Why some breast cancers evade treatment: Protein secreted by T cells may explain resistant ...
Up to 20% of hormone receptor-positive breast cancers don't respond to antiestrogen therapies. A study led by researchers at ...
Fusobacterium nucleatum can drive DNA damage, tumor growth and metastasis, with heightened effects in cells with BRCA1 gene mutations.
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