天然生物模板由于其精确的分子排列和良好的生物相容性,逐渐成为构建功能材料的重要基础。其中,丝状M13噬菌体凭借其高度规则的衣壳蛋白结构、丰富的可修饰位点以及稳定的遗传机制,长期被用作多功能生物纳米模板。为使其进一步适应不同应用场景,对其进行定制化改造至关重要。
这项发表在 Nature Biotechnology 上的工作,通过单次 AAV 注射在活体中实现了显著的酶活性恢复。这为未来的临床试验提供了新的思路:或许我们不再需要针对每种病单独开发药物,而是可以采用“篮子试验”(Basket Trial) 设计——不管患有哪种遗传病,只要基因检测显示“UGA 无义突变”,就有望进入同一个治疗篮子。
Minister for Information Technology, Biotechnology and Rural Development Priyank Kharge said the state will unveil an Ocean Farming Policy, back AI–biotech convergence, and push a greener data ...
In nanoscale particle research, precise control and separation have long been a bottleneck in biotechnology. Researchers at the University of Oulu have now developed a new method that improves ...
Experts highlight biotechnology's potential to drive sustainable growth and career opportunities in India's emerging ...
VIR-5500 ASCO GU update, VIR-5818 H2’26, ECLIPSE 1 Q4’26 + more hepatitis delta readouts. See more details here.
This board strengthens Serpin Pharma’s ability to advance innovative immune‑modulating therapeutics and expand our ...
Biotechnology is the exploitation of biological processes for the development of technologies and products for a specific use. GlobalData’s Strategic Intelligence report on biotech details how recent ...
The biotechnology market is entering a new growth phase, driven by the convergence of genomic science, artificial intelligence, and precision medicine, as global R&D investment approaches $360 billion ...
根据NCI泌尿生殖系恶性肿瘤科助理研究医师Melissa Abel博士所展示的数据,联合疗法显示PSA中位数下降40%,16名患者中有6名达到了超过50%的下降。无进展生存期范围为4.3至32.2个月。
引言 我们长期信奉着一条近乎真理的中心法则:DNA转录为mRNA,mRNA翻译为蛋白质。在这种线性的逻辑下,mRNA往往被视为蛋白质的忠实代理人。过去十年,单细胞测序技术(scRNA-seq)的爆发,让我们习惯于通过统计mRNA的数量来推断细胞的功能状态,仿佛掌握了剧本(转录本),就等于看到了演出(蛋白质功能)。 然而,剧本真的等于演出吗?